The biochemistry of Dupuytren's disease.

Badalamente, M A; Hurst, L C · Hand Clin · 1999

review · Level V

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Abstract

The molecular biochemical aspects of Dupuytren's disease have been studied for decades. This article summarizes biochemical influences on myofibroblast contractility, endogenous and exogenous chemical regulation, the influence of growth factors, and the biochemistry of collagen. A clear insight into the biochemistry of Dupuytren's disease may provide a foundation for future clinical interventions.

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