Application of distance geometry to 3D visualization of sequence relationships.
basic_science · Level V
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- Record sourced from PubMed, PMID 10068697.
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Abstract
We describe the application of distance geometry methods to the three-dimensional visualization of sequence relationships, with examples for mumps virus SH gene cDNA and prion protein sequences. Sequence-sequence distance measures may be obtained from either a multiple sequence alignment or from sets of pairwise alignments. C/Perl code and HTML/VRML files from http://www.nibsc.ac.uk/dg3dseq/
Medical subject headings
- Computer Simulation
- Models, Molecular
- Sequence Alignment