Clinical manifestations of the release of histamine and other inflammatory mediators.

Naclerio, R · J Allergy Clin Immunol · 1999

review · Level V

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Abstract

This article reviews the symptoms that are characteristic of the early- and late-phase allergic reaction. Each of the cardinal symptoms of seasonal allergic rhinitis (sneezing, pruritus, rhinorrhea, congestion) is discussed, as is the role of various chemical mediators in the expression of these clinical manifestations.

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