Influence of weight gain on spine mineral density in postmenopausal women.

Abstract

We studied the relationships between weight variables and spine bone mineral density (BMD) in 183 postmenopausal women aged 34-76 years. There was a significant positive correlation of current body mass index (cBMI) and % of ideal body weight (IBW) with BMD. Moreover, the increase in BMI and % IBW was also positively and significantly associated with a higher age-adjusted lumbar BMD. Weight gain, estimated as the difference between current body weight and past "ideal" body weight, was associated with significant age-adjusted BMD with a threshold of 17%, and postmenopausal women with a gain of over 17% had significantly higher spine BMD.