Severe anaphylactic reaction after primary exposure to aprotinin.
case_report · Level V
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- Record sourced from PubMed, PMID 10215242.
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Abstract
Aprotinin is widely used to prevent bleeding and reduce blood transfusions after open heart surgical procedures. Because it is a foreign protein, aprotinin has allergenic potential. We report a case of near-fatal anaphylactic reaction to primary aprotinin exposure in a child successfully treated using cardiopulmonary bypass support. The possibility of an allergic reaction must be considered whenever this drug is used.
Medical subject headings
- Anaphylaxis
- Aprotinin
- Hemostatics