Energy transduction in the sodium F-ATPase of Propionigenium modestum.

Dimroth, P; Wang, H; Grabe, M; Oster, G · Proc Natl Acad Sci U S A · 1999

basic_science · Level V

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Abstract

The F-ATPase of the bacterium Propionigenium modestum is driven by an electrochemical sodium gradient between the cell interior and its environment. Here we present a mechanochemical model for the transduction of transmembrane sodium-motive force into rotary torque. The same mechanism is likely to operate in other F-ATPases, including the proton-driven F-ATPases of Escherichia coli.

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