Mannitol and frusemide in the treatment of diuretic resistant oedema in nephrotic syndrome.
case_report · Level V
Where this comes from
- Record sourced from PubMed, PMID 10325739.
- Also identified by PMC identifier 1717829.
- No licence information is recorded for this record.
- Because redistribution is not established, this page shows the abstract only. Follow the links below for the full text.
Abstract
Three children (two girls aged 7 and 9 years, and one boy aged 4 years) with diuretic resistant oedema in steroid resistant nephrotic syndrome were treated with a combination of intravenous mannitol and frusemide. All three responded with loss of oedema of 10% to 30% of body weight over one week. There were no complications of hypertension or hypovolaemia. Mannitol-frusemide combination is a safe, inexpensive, and effective treatment for diuretic resistant oedema. Its use in other conditions and in developing countries (where the availability and purity of 20% albumin is limited) needs to be explored.
Medical subject headings
- Diuretics
- Edema
- Furosemide
- Mannitol
- Nephrotic Syndrome