Respiratory distress due to minocycline-induced pulmonary lupus.

Christodoulou, C S; Emmanuel, P; Ray, R A; Good, R A; Schnapf, B M; Cawkwell, G D · Chest · 1999

case_report · Level V

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Abstract

Minoeycline, a semisynthetic tetracycline, is often used to treat acne and rheumatoid arthritis. It has been considered an unlikely drug to be associated with systemic lupus erythematosus; however, many cases of drug-induced lupus related to minocycline have been reported. Some of those reports included pulmonary lupus, but none of the patients described developed respiratory distress. We describe a patient treated with minocycline for 2 years who presented with progressive dyspnea, severe hypoxia, and pulmonary infiltrates necessitating hospitalization and oxygen supplementation.

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