Bowen's disease showing spontaneous complete regression associated with apoptosis.
case_report · Level V
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- Record sourced from PubMed, PMID 10354038.
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Abstract
Spontaneous regression is sometimes seen in malignant skin tumours. We report a 68-year-old woman whose Bowen's disease showed spontaneous complete regression. Prominent infiltration of T cells and increased vascularity were found in the upper dermis of the regressed lesion. Strong expression of Fas (APO-1/CD95) antigen, an apoptosis-related tumour necrosis factor receptor family protein, in the primary lesion and faint expression following regression suggest the involvement of Fas-mediated apoptosis in the spontaneous complete regression of our patient's Bowen's disease.
Medical subject headings
- Apoptosis
- Bowen's Disease
- Neoplasm Regression, Spontaneous
- Skin Neoplasms