Molecular biology for the critical care physician. Part II: where are we now?

Santis, G; Evans, T W · Crit Care Med · 1999

review · Level V

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Abstract

The extraordinary technical developments in molecular biology are having a profound impact in clinical medicine. The contribution of recombinant DNA technology in defining the molecular pathology of common disorders and of diagnostic molecular techniques for detection of infectious organisms are used as examples to demonstrate the clinical relevance of these developments. Finally, the potential use of DNA as a therapeutic drug (gene therapy) is addressed.

Medical subject headings