A pilot study of iron depletion as adjuvant therapy in chronic hepatitis C patients not responding to interferon.

Guyader, D; Boucher, E; André, P; Even, C; Cottereau, J; Bianchi, A; Gasser, P; Mendler, M H et al. · Am J Gastroenterol · 1999

case_series · Level IV

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Abstract

The aim of this study was to assess the efficacy of iron depletion obtained by phlebotomy to enhance interferon response in 11 patients who had failed to respond to a standard 3-month interferon treatment. Despite a significant effect on serum aminotransferase levels, there was no effect on viremia, and iron depletion was unable to trigger interferon response.

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