Impact of localized radiotherapy on blood immune cells counts and function in humans.
prospective_cohort · Level II
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Abstract
Immune cells subsets were prospectively analyzed after localized radiotherapy (LRT). LRT reduced the levels of all lymphocyte subsets, with B-cells and naive T-cells being most sensitive. Lymphocyte function was suppressed, but still within the normal range. Rapid recovery of cytotoxic T-cells/natural killer cells after LRT and the functional suppression within normal levels explains the low incidence of infections after LRT.
Medical subject headings
- B-Lymphocytes
- Lymphocyte Subsets
- Seminoma
- T-Lymphocytes
- Testicular Neoplasms