Triple pituitary adenoma in Cushing's disease: case report.
case_report · Level V
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Abstract
A case of a triple pituitary adenoma identified in a surgically removed pituitary gland from a 52-year-old woman operated on for Cushing's disease is presented. The histology revealed 3 distinctly separate microadenomas, 1 corticotroph and 2 immunoreactive for prolactin (PRL). The latter were apparently silent, since the serum PRL levels were within normal range. The problems associated with the inability to identify multiple adenomas pre-operatively and the possible failure of selective transsphenoidal adenomectomy in case of multiple adenomas are emphasised.
Medical subject headings
- Adenoma, Basophil
- Cushing Syndrome
- Neoplasms, Multiple Primary
- Pituitary Neoplasms
- Prolactinoma