Multiple cerebral infarctions associated with ovarian hyperstimulation syndrome.

Yoshii, F; Ooki, N; Shinohara, Y; Uehara, K; Mochimaru, F · Neurology · 1999

case_report · Level V

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Abstract

A 26-year-old woman on human menopausal gonadotrophin-human chorionic gonadotrophin therapy for sterility showed multiple cerebral infarctions associated with ovarian hyperstimulation syndrome. A hypercoagulable state (hemoconcentration, increased plasma levels of D-dimer and thrombin-antithrombin III complex, and decreased protein S activity) was associated with her thromboembolic events. Cerebral infarction associated with mild neurologic deficits may be overlooked in patients with ovarian hyperstimulation syndrome.

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