Severe immune hemolytic anemia associated with prophylactic use of cefotetan in obstetric and gynecologic procedures.
case_report · Level V
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Abstract
Second- and third-generation cephalosporins, especially cefotetan, are increasingly associated with severe, sometimes fatal immune hemolytic anemia. We noticed that 10 of our 35 cases of cefotetan-induced hemolytic anemias were in patients who had received cefotetan prophylactically for obstetric and gynecologic procedures. Eight of these cases of severe immune hemolytic anemia are described.
Medical subject headings
- Anemia, Hemolytic, Autoimmune
- Antibiotic Prophylaxis
- Cefotetan
- Cephamycins