Paraneoplastic cicatricial pemphigoid.
case_report · Level V
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- Record sourced from PubMed, PMID 10417528.
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Abstract
We report a 39-year-old woman with antiepiligrin cicatricial pemphigoid (CP) in association with non-small cell carcinoma of the lung. At presentation, mucosal lesions showed minimal response to combined systemic immunosuppressive agents. Following the diagnosis of non-small cell lung carcinoma and subsequent treatment with gemcitabine (a second-line chemotherapeutic agent), a significant reduction in both tumour mass and mucosal blistering was observed. Metastatic disease was subsequently associated with recurrent oral erosions. We believe this patient represents the first reported case of paraneoplastic CP.
Medical subject headings
- Carcinoma, Non-Small-Cell Lung
- Lung Neoplasms
- Paraneoplastic Syndromes
- Pemphigoid, Benign Mucous Membrane
- Skin