Longitudinal, transverse, and diffuse nail hyperpigmentation induced by hydroxyurea.

Hernández-Martín, A; Ros-Forteza, S; de Unamuno, P · J Am Acad Dermatol · 1999

case_report · Level V

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Abstract

Hydroxyurea is a cytostatic agent used in patients with myeloproliferative disorders that may produce nail hyperpigmentation, most frequently longitudinal melanonychia. We present a patient treated with hydroxyurea whose nails showed several patterns of nail hyperpigmentation, including longitudinal and transverse bands, and a diffuse darkening of the nail matrix.

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