Effect of an alpha(2) agonist (mivazerol) on limiting myocardial ischaemia in stable angina.
prospective_cohort · Level II
Where this comes from
- Record sourced from PubMed, PMID 10455094.
- Also identified by PMC identifier 1729187.
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Abstract
A specific alpha(2) agonist, mivazerol, known to be effective in reducing myocardial ischaemia when given intravenously immediately before an exercise tolerance test, produced a significant increase in exercise duration and time to the onset of angina when given orally over a two week period to 25 patients with stable angina. A non-significant trend to reduction in electrocardiographic signs of ischaemia was also noted. The clinical relevance of this improvement now needs to be tested in larger numbers.
Medical subject headings
- Adrenergic alpha-Agonists
- Angina Pectoris
- Imidazoles