Corneal endothelial changes in patients with chronic renal failure.

Ohguro, N; Matsuda, M; Fukuda, M · Am J Ophthalmol · 1999

case_control · Level III

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Abstract

To evaluate the morphologic changes of the corneal endothelium in patients with chronic renal failure. Twenty corneas of 20 patients with chronic renal failure undergoing hemodialysis were examined by wide-field specular microscopy. Twenty normal corneas from 20 healthy age-matched subjects were enrolled as control corneas. Despite normal endothelial cell density, the corneal endothelium of patients with chronic renal failure showed marked polymegethism and pleomorphism. Polymegethism and pleomorphism of the corneal endothelium are found in patients with chronic renal failure.

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