Noninfectious crystalline keratopathy after postoperative subconjunctival 5-fluorouracil.
case_report · Level V
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Abstract
To describe a case of transient, noninfectious crystalline keratopathy after postoperative subconjunctival 5-fluorouracil. Case report. Slit-lamp biomicroscopic examinations were performed during serial office examinations. A 69-year-old woman underwent an uncomplicated trabeculectomy with adjunctive sponge 5-fluorouracil application for 5 minutes in her left eye. Postoperative treatment included topical prednisolone acetate, ciprofloxacin, and scopolamine. She was initially examined with intrastromal corneal crystalline deposits 5 days after her first postoperative subconjunctival injection of 5-fluorouracil. The deposits completely disappeared 4 days later without addition to or change in treatment. Transient, noninfectious, crystalline, intrastromal corneal deposits may develop after adjunctive subconjunctival 5-fluorouracil administration.
Medical subject headings
- Antimetabolites
- Cornea
- Corneal Diseases
- Fluorouracil