Hormone replacement therapy and sensitive C-reactive protein concentrations in women with type-2 diabetes.

Sattar, N; Perera, M; Small, M; Lumsden, M A · Lancet · 1999

rct · Level II

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Abstract

C-reactive protein concentrations as a marker of inflammation predicts vascular risk and is raised in type-2 diabetes. In a 6-month double-blind placebo controlled trial, a combination of transdermal oestradiol 80 microg with continuous oral norethisterone 1 mg significantly reduced C-reactive protein concentrations in postmenopausal women with type-2 diabetes.

Medical subject headings