Prophylactic antibiotics and endocervical microbial inoculation of the endometrium at embryo transfer.

Egbase, P E; Udo, E E; Al-Sharhan, M; Grudzinskas, J G · Lancet · 1999

retrospective_cohort · Level III

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Abstract

Prophylactic antibiotics administered routinely to women at the time of oocyte retrieval were associated with a reduction in positive microbiology cultures of embryo catheter tips 48 h later in 78.4% of patients. The implantation and clinical pregnancy rates were significantly lower (9.3% vs 21.6%, p<0.001; 18.7% vs 41.3%, p<0.01) in the women with positive microbial catheter-tip cultures.

Medical subject headings