Therapeutic implications of the sentinel lymph node in breast cancer.

McIntosh, S A; Going, J J; Soukop, M; Purushotham, A D; Cooke, T G · Lancet · 1999

case_series · Level IV

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Abstract

Immunohistochemistry of histologically negative axillary lymph nodes in breast-cancer patients resulted in upstaging of the sentinel lymph node in eight (14%) of 52 patients. The resulting information altered clinical management in six of these patients. Thus, this technique may affect clinical decision-making in breast-cancer patients.

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