Acute effect of nitric oxide on Raynaud's phenomenon in scleroderma.

Freedman, R R; Girgis, R; Mayes, M D · Lancet · 1999

rct · Level II

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Abstract

Intra-arterial infusions of L-arginine and sodium nitroprusside significantly decreased the occurrence of laboratory-induced Raynaud's phenomenon in scleroderma patients. Raising the concentration of nitric oxide may be of therapeutic value in this population.

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