Importance of levonorgestrel dose in oral contraceptives for effects on coagulation.

Kluft, C; de Maat, M P; Heinemann, L A; Spannagl, M; Schramm, W · Lancet · 1999

expert_opinion · Level V

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Abstract

Combined oral contraceptives show clear differences in effect on the tissue factor-initiated coagulation test of activated protein C resistance, which is dependent on the presence and dosage of levonorgestrel. Multiphasic levonorgestrol oral contraceptives differ from monophasic contraceptives and resemble third-generation contraceptives.

Medical subject headings