Reversible pancreatitis, hepatitis, and peripheral polyneuropathy associated with parenteral gold therapy.
case_report · Level V
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- Record sourced from PubMed, PMID 10493691.
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Abstract
A 63-year-old man with seronegative rheumatoid arthritis developed acute pancreatitis, severe hepatitis, and sensorimotor polyneuropathy after receiving 150 mg of intramuscular aurothioglucose (gold). Positive lymphocyte transformation test to gold indicated a cell mediated hypersensitivity to the drug, while multiple investigations ruled out other underlying causes for his illness. After cessation of gold therapy a complete recovery occurred.
Medical subject headings
- Arthritis, Rheumatoid
- Chemical and Drug Induced Liver Injury
- Drug Hypersensitivity
- Gold Compounds
- Pancreatitis
- Peripheral Nervous System Diseases