Encephalopathy in scleromyxedema.
case_report · Level V
Where this comes from
- Record sourced from PubMed, PMID 10496284.
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Abstract
The authors monitored CSF findings for over 5 months in a patient with a fatal case of scleromyxedema and two episodes of encephalopathy. During both encephalopathy episodes, CSF protein and immunoglobulin G (IgG) levels were elevated without an increased IgG index or IgG synthesis rate. A CSF-dominant increase in the concentration of interleukin-6 (IL-6) also was noted during encephalopathy. These findings suggest a disruption of the blood-brain barrier and that IL-6 may play some role in mediating the encephalopathy. OFF
Medical subject headings
- Brain Diseases
- Mucinoses
- Myxedema