K-Estimator: calculation of the number of nucleotide substitutions per site and the confidence intervals.
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Abstract
K-Estimator 4.5 is a Windows program that estimates the number of nucleotide substitutions per site (divergence) when comparing two aligned nucleotide sequences, both protein-coding and non-coding. Confidence intervals of the divergence estimates are obtained by Monte Carlo simulation. The program is available for non-profit use via anonymous ftp at ftp.bio.indiana. edu/molbio/mswin. jcomeron@midway.uchicago.edu
Medical subject headings
- DNA Mutational Analysis
- Proteins
- Sequence Alignment
- Software