Has advice on periconceptional folate supplementation reduced neural-tube defects?

Abramsky, L; Botting, B; Chapple, J; Stone, D · Lancet · 1999

editorial · Level V

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Abstract

Periconceptional folate supplementation has been encouraged in the UK since the early 1990s, but no concurrent decline in neural-tube-defect pregnancies has been observed by regional congenital anomaly registers.

Medical subject headings