Oxidative stress mediates apoptosis induced by oxidized low-density lipoprotein and oxidized lipoprotein(a).
basic_science · Level V
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Abstract
We measured oxidative stress caused by lipoproteins in human umbilical vein endothelial cells and rabbit aorta. Oxidized lipoprotein(a) was the more potent stimulus over oxidized low density lipoprotein, and we believe that both influence the pathogenesis of atherosclerosis.
Medical subject headings
- Apoptosis
- Lipoprotein(a)
- Lipoproteins, LDL
- Oxidative Stress