Low-dose subcutaneous ketamine infusion and morphine tolerance.
case_report · Level V
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- Record sourced from PubMed, PMID 10506678.
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Abstract
The NMDA receptor has been reported to be involved in opioid tolerance. Adjuvant subcutaneous infusion treatment with (very) low-dose ketamine, a NMDA receptor antagonist, improves analgesia and at the same time appears to reduce morphine tolerance. Three cases are presented.
Medical subject headings
- Analgesics
- Ketamine
- Intractable Pain