Total hypotrichosis: genetic form of alopecia not linked to hairless gene.
basic_science · Level V
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Abstract
We describe a hereditary form of alopecia in an aboriginal Finno-Ugric population. Linkage and mutation analyses of 21 families showed that the disorder was not linked to the hairless gene on chromosome 8. This implies that an isolated hairless defect caused by a single gene is a genetically heterogeneous disorder in human populations.
Medical subject headings
- Alopecia