Postpartum cerebellar herniation in von Hippel-Lindau syndrome.

Othmane, I S; Shields, C; Singh, A; Shields, J; Goldman, W · Am J Ophthalmol · 1999

case_report · Level V

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Abstract

To describe exacerbation during pregnancy of cerebellar hemangioblastoma in von Hippel-Lindau syndrome. Case-report. A 21-year-old woman with von Hippel-Lindau syndrome was found on routine ocular examination to have severe papilledema 1 week after giving birth. Immediate magnetic resonance imaging disclosed a large cerebellar cyst from hemangioblastoma causing cerebellar tonsillar herniation. Immediate neurosurgical intervention was life saving. Worsening of intracranial hemangioblastoma during pregnancy in cases of von Hippel-Lindau syndrome should be realized and periodic neurologic and ophthalmologic observation is warranted.

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