Intoxication due to negative canrenone interference in digoxin drug monitoring.
case_report · Level V
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- Record sourced from PubMed, PMID 10513714.
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Abstract
Canrenone and spironolactone caused falsely low readings in a common assay for digoxin (AxSym MEIA) due to negative cross-reactivity. Misleading subtarget concentrations were repeatedly reported, and falsely guided drug dosing resulted in a case of digoxin intoxication.
Medical subject headings
- Canrenone
- Digoxin
- Drug Monitoring
- Medication Errors
- Spironolactone