Association of CCR5 delta32 with reduced risk of asthma.

Hall, I P; Wheatley, A; Christie, G; McDougall, C; Hubbard, R; Helms, P J · Lancet · 1999

case_report · Level V

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Abstract

We report that individuals carrying the CCR5 delta32 mutation, a naturally occurring variant of the C-C chemokine receptor 5 (CCR5), are at reduced risk of developing asthma. These data suggest a possible explanation for the high prevalence of this mutation in the general population.

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