Necrobiotic cutaneous T-cell lymphoma.
case_report · Level V
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- Record sourced from PubMed, PMID 10534657.
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Abstract
We report 3 patients with granulomatous cutaneous T-cell lymphoma (CTCL) who showed necrobiosis histologically with palisading granulomas. Although granulomatous change may be present in up to 4% of cases of CTCL, necrobiosis is rare. Misdiagnosis may occur if epidermotropism is minimal or if atypical cells are masked by the granulomatous infiltrate. T-cell receptor gene analysis confirmed the presence of clonal T-cell populations in lesional skin from all 3 cases.
Medical subject headings
- Lymphoma, T-Cell, Cutaneous
- Skin Neoplasms