The great escape - AIDS viruses and immune control.

Goulder, P J; Walker, B D · Nat Med · 1999

editorial · Level V

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Abstract

Many studies have been designed to address the role of CTL immune escape in HIV-1 infection, but have not given conclusive answers. Now, an elegant longitudinal analysis clearly demonstrates that progression to disease in SIV-infected macaques is associated with evasion of the CTL response (pages 1270-1276).

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