Inflammatory thoughts about glioma gene therapy.
editorial · Level V
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- Record sourced from PubMed, PMID 10545984.
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Abstract
Gene therapy for treatment of glioma often involves delivery of herpes simplex virus-1 thymidine kinase gene. A new study shows that this approach can induce chronic inflammation, and raises important questions about current adenoviral-based clinical trials (pages 1256-1263).
Medical subject headings
- Brain Neoplasms
- Encephalitis
- Genetic Therapy
- Glioma