Cerebral vasoreactivity to arterial carbon dioxide tension in preterm infants: the effect of ibuprofen.

Mosca, F; Bray, M; Colnaghi, M R; Fumagalli, M; Compagnoni, G · J Pediatr · 1999

other · Level V

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Abstract

Cerebral vasoreactivity to CO(2), calculated by linear regression of total cerebral hemoglobin, measured by near infrared spectroscopy, and corresponding PaCO(2), in infants <32 weeks' gestation, was found to be unaffected by the administration of ibuprofen, which was given on the first postnatal day as prophylaxis against patent ductus arteriosus.

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