Polymorphisms within the interleukin-10 receptor cDNA gene (IL10R) in Japanese patients with systemic lupus erythematosus.
case_control · Level III
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Abstract
To assess the association between polymorphisms within the interleukin-10 receptor cDNA gene (IL10R) and systemic erythematosus (SLE) in Japanese people. We examined the IL-10 receptor genotype of 109 SLE patients and 102 healthy subjects by the reverse transcription-polymerase chain reaction-restriction fragment length polymorphism (RT-PCR-RFLP) method. There was no difference in the IL10R genotype frequencies of these two groups. The IL10R genotype does not determine susceptibility to SLE in Japanese people.
Medical subject headings
- Lupus Erythematosus, Systemic
- Polymorphism, Genetic
- Receptors, Interleukin