Juvenile Parkinson's disease with REM sleep behavior disorder, sleepiness, and daytime REM onset.
case_report · Level V
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- Record sourced from PubMed, PMID 10563644.
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Abstract
We describe an unmedicated patient with juvenile PD with difficulties maintaining wakefulness and the atonia of REM sleep. Laboratory testing showed enhanced muscle activity in REM sleep consistent with a history of dream enactment behavior (i.e., REM sleep behavior disorder) and daytime sleepiness, and REM-sleep onsets on multiple sleep latency testing. The results emphasize the potential role of dopamine and basal ganglia circuits in the modulation of activated behavioral states (e.g., wakefulness and REM sleep).
Medical subject headings
- Adolescent Behavior
- Circadian Rhythm
- Parkinson Disease
- REM Sleep Behavior Disorder
- Sleep Stages
- Sleep, REM