Cellular prion protein expressed by bovine squamous epithelia of skin and upper gastrointestinal tract.
basic_science · Level V
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Abstract
Routes of transmission of bovine spongiform encephalopathy have not yet been determined. We show that bovine squamous epithelia of the skin and upper gastrointestinal tract express Prp(c), suggesting that these epithelia may be a target for prion entry and replication.
Medical subject headings
- Digestive System
- Encephalopathy, Bovine Spongiform
- Epithelial Cells
- PrPC Proteins
- Skin