Keratotsis punctata of the palmar creases: report of two cases associated with ichthyosis vulgaris.
case_report · Level V
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Abstract
Two patients with keratosis punctata of the palmar creases are described. The association with ichthyosis vulgaris and other disorders of keratinization is discussed. In both cases, histopathology revealed a close relation between the keratotic plug and the sweat glands. The role of genetic factors and manual activity in the pathogenesis is discussed. Treatment with oral etretinate resulted in a good improvement in the first patient, but prolonged low-dose maintenance therapy was required to prevent recurrence.
Medical subject headings
- Hand Dermatoses
- Ichthyosis Vulgaris
- Keratosis