Surface micropatterning to regulate cell functions.

Ito, Y · Biomaterials · 1999

review · Level V

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Abstract

The current technology available for surface microfabrication with macromolecules to regulate cell functions is reviewed. Surface topology, and surface modification with hydrophilic or hydrophobic polymers, electrically charged polymers, stimuli-responsive macromolecules, polysaccharide, and proteins involving adhesion or growth factors are discussed. These surface-microfabricatec biomaterials had the ability to regulate cell functions such as proliferation, differentiation, and apoptosis.

Medical subject headings