Linkage disequilibrium and recombination in hominid mitochondrial DNA.

Awadalla, P; Eyre-Walker, A; Smith, J M · Science · 1999

editorial · Level V

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Abstract

The assumption that human mitochondrial DNA is inherited from one parent only and therefore does not recombine is questionable. Linkage disequilibrium in human and chimpanzee mitochondrial DNA declines as a function of the distance between sites. This pattern can be attributed to one mechanism only: recombination.

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