Clinical and magnetic resonance imaging findings in chronic sensory ganglionopathies.

Lauria, G; Pareyson, D; Grisoli, M; Sghirlanzoni, A · Ann Neurol · 2000

case_series · Level IV

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Abstract

Twenty-two of 29 patients with chronic sensory ataxic neuropathy showed T2-weighted magnetic resonance imaging high signal intensity in the posterior columns of the cervical spine. T2 changes reflected the degeneration of central sensory projections and localized the disease process to T-shaped dorsal root ganglion neurons. No similar abnormalities were found in sensory and sensorimotor length-dependent axonal neuropathy patients. Spinal cord magnetic resonance imaging is a useful tool to support the clinical diagnosis of primary ganglionopathy.

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