Gallstones in sickle cell disease: observations from The Jamaican Cohort study.
prospective_cohort · Level II
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Abstract
The prevalence, incidence, risk factors, clinical associations, and morbidity of gallstones were studied in 311 patients with homozygous sickle cell disease and 167 patients with sickle cell-hemoglobin C disease in a cohort study from birth. Gallstones developed in 96 patients with homozygous sickle cell disease and 18 patients with sickle cell-hemoglobin C disease; specific symptoms necessitating cholecystectomy occurred in only 7 patients with homozygous sickle cell disease.
Medical subject headings
- Anemia, Sickle Cell
- Cholelithiasis
- Hemoglobin SC Disease