Human carcinoma: early experience with phase-contrast X-ray CT with synchrotron radiation--comparative specimen study with optical microscopy.
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Abstract
Phase-contrast x-ray computed tomography (CT) indicates the distribution of the refractive index and has potential to reveal the structures inside soft tissues without a contrast agent. With a synchrotron x-ray source, phase-contrast x-ray CT with a triple Laue-case x-ray interferometer clearly differentiated various human pathologic tissues in the cases of hepatocellular carcinoma with cirrhosis and metastatic colon carcinoma to the liver, and the images closely corresponded to those obtained with low-magnification optical microscopy.
Medical subject headings
- Carcinoma, Hepatocellular
- Colonic Neoplasms
- Liver Cirrhosis
- Liver Neoplasms
- Radiographic Image Enhancement
- Synchrotrons
- Tomography, X-Ray Computed