Major depression is a risk factor for seizures in older adults.
case_control · Level III
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- Record sourced from PubMed, PMID 10665498.
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Abstract
We tested the hypothesis that major depression meeting DSM-III-R criteria or medical therapies for depression increase the risk for unprovoked seizures. Major depression was associated with a sixfold increased risk for unprovoked seizures (95% CI, 1.56-22). The risk remained increased even when controlling for age, sex, length of medical follow-up, and medical therapies for depression. In the absence of known prior neurological insult, major depression is associated with an increased risk for unprovoked seizures.
Medical subject headings
- Aging
- Major Depressive Disorder
- Seizures