New immunopharmacologic approaches to asthma: role of cytokine antagonism.

Rosenwasser, L J · J Allergy Clin Immunol · 2000

review · Level V

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Abstract

This article involves an elucidation of the potential inflammatory mechanisms associated with the treatment of allergic disease and asthma, and the possibility of cytokine antagonism as a potential therapeutic mechanism for the treatment of those diseases. There is a review of the role of cytokines in the allergic process and a description of a number of studies done with the capacity of certain cytokine antagonists to develop potential amelioration of immune dysregulation in asthma and atopic states.

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